CANDESARTAN 4MG (100 TABLETS)

Generic Name: candesartan
Brand Name: Atacand
Drug class: Angiotensin receptor blockers

Atacand and its generic candesartan is available in the strength of 4 mg and 8 mg and 16 mg and 32 mg tablets.

Candesartan belongs to a family of medications known as angiotensin II receptor blockers and are used to treat high blood pressure, prevent mild-to-moderate congestive heart failure, or decrease the risk of further heart attack occurrences in people with coronary artery disease. High blood pressure adds to the workload of the heart and arteries. If the additional workload is untreated or left unmanaged, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart or kidney failure.

Candesartan works to relax veins and arteries allowing for smoother blood flow thus lower blood pressure by preventing an enzyme in the body from producing angiotensin II, a substance that narrows blood vessels. As a result, blood vessels stay relaxed allowing for an adequate supply of blood and oxygen to the heart that will lower blood pressure.

It takes about 2 weeks for this medication to begin lowering blood pressure, and about 4 weeks for it to reach its full effect.

This medication should not be used in children less than 1 year of age.

For adults with high blood pressure, the usual recommended starting dose of candesartan is 16 mg once daily. Reductions in blood pressure are often seen within 2 weeks, and the full effects on blood pressure are seen in about 4 weeks. Your doctor may decide to increase the dose to 32 mg once a day if your blood pressure has not decreased enough. A diuretic (water pill) may also be added to help reduce blood pressure.

For children with high blood pressure, the dose of candesartan is based on body weight. The usual starting dose for children weighing less than 50 kg is 4 mg once daily. This dose may be increased to a maximum daily dose of 8 mg. For children weighing more than 50 kg, the usual starting dose is 8 mg once daily. This dose may be increased to a maximum daily dose of 16 mg.

For adults with heart failure the usual recommended starting dose of candesartan is 4 mg once daily. Depending on how well you tolerate the medication, the dose may be doubled every 2 weeks to a maximum daily dose of 32 mg.

Candesartan should be taken at approximately the same time each day, with or without food.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose but remember within 12 hours, take it as soon as possible and continue with your regular schedule. If more than 12 hours have passed since your usual dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

It is important to take this medication regularly and to follow your doctor's instructions regarding monitoring your blood pressure to ensure that you receive the maximum benefit from the medication.

Store this medication at room temperature (in a dry place and not in the bathroom) in its original package and keep it out of the reach of children. Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Do not take candesartan if you:

• are allergic to candesartan or any of the ingredients of the medication

• are or plan to become pregnant

• are breastfeeding

• have diabetes or moderate-to-severe kidney disease and are taking the medication aliskiren

• have galactose intolerance or glucose malabsorption (a rare hereditary disease)

• are on any of the following medications:

  • aldesleukin

  • alpha-blockers (e.g., alfuzosin, doxazosin, tamsulosin)

  • alpha-agonists (e.g., clonidine, methyldopa)

  • aliskiren

  • amiodarone

  • amphetamines (e.g., dextroamphetamine, lisdexamfetamine)

  • angiotensin-converting enzyme inhibitors (ACEIs; captopril, enalapril, ramipril)

  • antipsychotics (e.g., chlorpromazine, clozapine, olanzapine, quetiapine, risperidone)

  • apomorphine

  • barbiturates (e.g., butalbital, phenobarbital)

  • beta-adrenergic blockers (e.g., atenolol, propranolol, sotalol)

  • brimonidine

  • bromocriptine

  • calcium channel blockers (e.g., amlodipine, diltiazem, nifedipine, verapamil)

  • celecoxib

  • certain cancer-treating medications (e.g., arsenic trioxide, clofarabine, paclitaxel)

  • conivaptan

  • dexmethylphenidate

  • diuretics (water pills; e.g., furosemide, hydrochlorothiazide, triamterene)

  • drospirenone

  • duloxetine

  • eplerenone

  • guanfacine

  • heparin

  • levodopa

  • lithium

  • low-molecular-weight heparins (e.g., dalteparin, enoxaparin, tinzaparin)

  • methylphenidate

  • minoxidil

  • monoamine oxidase inhibitors (MAOIs; e.g., phenelzine, rasagiline, selegiline, tranylcypromine)

  • morphine

  • nabilone

  • nitrates (e.g., nitroglycerin, isosorbide dinitrate, isosorbide mononitrate)

  • nonsteroidal anti-inflammatory drugs (NSAIDs; e.g., naproxen, ibuprofen)

  • obinutuzumab

  • other angiotensin receptor blockers (ARBs; e.g., irbesartan, losartan)

  • pentoxifylline

  • phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil, vardenafil)

  • potassium supplements or medications that increase potassium in the blood

  • riociguat

  • ropinirole

  • sacubitril

  • sodium phosphates

  • sotalol

  • tacrolimus

  • tizanidine

  • tolvaptan

  • tretinoin

  • tricyclic antidepressants (e.g., clomipramine, imipramine, trimipramine)

  • trimethoprim

This medication should not be used in children less than 1 year of age.

Possible side effects include:

• back or leg pain

• cold symptoms (e.g., nasal or head congestion, ear congestion or pain, runny or stuffy nose, sneezing)

• cough

• diarrhea

• dizziness

• drowsiness

• dry mouth

• fever

• headache

• muscle cramps

• sore throat

• trouble sleeping

• vomiting

• chest pain

• confusion

• dizziness, lightheadedness, or fainting

• fast, slow, or irregular heartbeat

• rash

• shortness of breath

• signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don't stop bleeding)

• signs of kidney problems (e.g., increased urination at night, decreased urine production, blood in the urine)

• signs of kidney failure (e.g., decreased urine production, swelling, fatigue, abdominal pain)

• signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)

• signs of pancreatitis (e.g., abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, swollen abdomen)

• signs of pneumonia (e.g., fever, chills, shortness of breath, cough)

• signs of too much potassium in the body (e.g., irregular heartbeat, muscle weakness, generally feeling unwell)

• unexplained muscle pain, tenderness, or weakness

© 2023 Arcedpharmas is the registered trademark used under license from YYOUNG Trademark Ltd. All material copyright MediResource Inc. 1996 – 2023. Terms and conditions of use. The contents herein are for informational purposes only. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Source: www.medbroadcast.com/drug/getdrug/ACH-Candesartan

Disclaimers: The images used on this website are for reference only. The product images shown may represent the range of product, or be for illustration purposes only and may not be an exact representation of the product.

Any returns of a product due to customer dissatisfaction will need to comply with the © 2023 Arcedpharmas Returns Policy.

CRESTOR 40MG BLSPK  (30 TABLETS)

Generic Name: rosuvastatin
Brand Name: Crestor
Drug class: HMG-CoA Reductase Inhibitors, Lipid-Lowering Agents, Statins

WHAT IS THE DOSAGE OF THIS MEDICATION?

Crestor and its generic rosuvastatin is available in the strength of 5 mg, 10 mg, 20 mg, and 40 mg tablets.

WHAT IS THIS MEDICATION USED FOR?

Rosuvastatin belongs to the group of medications known as HMG CoA reductase inhibitors ("statins"). It is used, along with a healthy diet and exercise program, to improve cholesterol levels by decreasing low-density lipoprotein (LDL) cholesterol ('bad cholesterol') and triglycerides in the blood, and increasing high-density lipoprotein (HDL) cholesterol ('good cholesterol') in the blood. It is also used to treat people who have certain inherited cholesterol disorders.

Rosuvastatin works by blocking the enzyme that helps make cholesterol in the body. People with high blood cholesterol levels have a higher risk of heart diseases such as heart attacks. When cholesterol levels are lowered with a combination of medication, diet, and exercise, the risk of heart disease is lowered. It takes 2 to 4 weeks to see the maximum effect of this medication on cholesterol levels in blood tests.

It can also be used to reduce the risk of heart attacks, stroke, and angioplasty for people who have at least 2 risk factors for cardiovascular disease.

Before starting rosuvastatin, you should be following a cholesterol-lowering diet. If appropriate, a program of weight control and physical exercise should also be implemented.

The recommended dose of rosuvastatin ranges between 5 mg and 40 mg once daily. For most people, the usual recommended starting dose of rosuvastatin is 10 mg once daily. If necessary, the dose may be increased to a maximum of 40 mg daily. People who require the maximum dose of 40 mg per day should consult a specialist.

For children 10 to 17 years of age, who have inherited cholesterol disorders, the recommended starting dose is 5 mg taken once daily. Your doctor may increase this dose to a maximum of 10 mg daily, depending on the effectiveness of the medication and how well it is tolerated.

For people with severely reduced liver function, the maximum daily dose is 20 mg.

For people with severely reduced kidney function, the starting dose should be 5 mg daily and the maximum daily dose is 10 mg.

A starting dose of 5 mg daily is recommended for people of Asian descent (Chinese, Filipino, Japanese, Korean, Vietnamese, or Asian-Indian origin) and those who have severe kidney problems. This low dose should also be considered for people who do not need aggressive cholesterol-lowering effects and for people who may be at a greater risk of experiencing muscle-related problems.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Rosuvastatin may be taken in the morning or in the evening, with or without food.

It is very important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and carry on with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children. Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

WHO SHOULD NOT TAKE THIS MEDICATION

Do not take rosuvastatin if you:

• are allergic to rosuvastatin or any ingredients of the medication

• are pregnant

• are breast-feeding

• are taking cyclosporine

• are taking the medications sofosbuvir/velpatasvir/voxilaprevir for chronic hepatitis C virus infection

• have active liver disease or have unexplained increases in certain liver function tests

Do not take the 40 mg strength of rosuvastatin if you:

• are of Asian descent (Chinese, Filipino, Japanese, Korean, Vietnamese, or Asian-Indian origin)

• are taking niacin or a fibrate (e.g., gemfibrozil, fenofibrate)

• have alcoholism or consume large quantities of alcohol

• have an inherited muscle disorder or a family history of these disorders

• have had muscle damage with another statin medication (e.g., lovastatin, pravastatin, simvastatin)

• have hypothyroidism (an underactive thyroid gland)

• have other medical conditions or are taking other medications that would increase blood levels of rosuvastatin (check with your doctor or pharmacist to see if this applies to you)

• have severely reduced liver or kidney function

  ---

POTENTIAL INTERACTION WITH OTHER MEDICATION

The following medications could potentially interact with rosuvastatin:

• antacids (if taken within 2 hours of taking rosuvastatin) (e.g., aluminum hydroxide, calcium carbonate, magnesium hydroxide)

• apalutamide

• bezafibrate

• carbamazepine

• clopidogrel

• cobicistat

• colchicine

• cyclosporine

• dronedarone

• elagolix

• eltrombopag

• eslicarbazepine

• fenofibrate

• gemfibrozil

• hepatitis C antivirals (e.g., glecaprevir and pibrentasvir, grazoprevir, ledipasvir, sofosbuvir, velpatasvir, voxilaprevir)

• HIV protease inhibitors (e.g., atazanavir, indinavir, ritonavir, saquinavir)

• itraconazole

• letermovir

• niacin (nicotinic acid)

• niacinamide

• pazopanib

• raltegravir

• regorafenib

• repaglinide

• rifampin

• other "statin" anti-cholesterol medications (e.g., atorvastatin, lovastatin, simvastatin)

• teriflunomide

• tolvaptan

• trabectedin

• warfarin

WHAT ARE THE SIDE EFFECTS OF THIS MEDICATION?

Possible side effects include:

• constipation

• decreased sexual ability

• difficulty sleeping

• dizziness

• headache

• nausea

• nightmares

• stomach pain

• breast enlargement

• confusion

• hives

• itching

• numbness, tingling, weakness, or pain in the hands or feet

• persistent cough, with or without shortness of breath

• poor memory

• signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don't stop bleeding)

• signs of depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)

• skin rash

• symptoms of high blood sugar (e.g., frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, fruity breath odour)

• symptoms of liver damage (such as yellow skin or eyes, abdominal pain, dark urine, clay-coloured stools, loss of appetite, nausea and vomiting, or itching)

• symptoms of muscle damage (unexplained muscle pain, tenderness or weakness, or brown or discoloured urine – especially if you also have a fever or a general feeling of being unwell)

• weakness

© 2023 Arcedpharmas is the registered trademark used under license from YYOUNG Trademark Ltd. All material copyright MediResource Inc. 1996 – 2023. Terms and conditions of use. The contents herein are for informational purposes only. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Source: www.medbroadcast.com/drug/getdrug/ACT-Rosuvastatin

Disclaimers: The images used on this website are for reference only. The product images shown may represent the range of product, or be for illustration purposes only and may not be an exact representation of the product.

Any returns of a product due to customer dissatisfaction will need to comply with the © 2023 Arcedpharmas Returns Policy.