COVERSYL 8MG  (30 TABS)

Generic Name: perindopril
Brand Name: Coversyl
Drug class: Angiotensin Converting Enzyme Inhibitors

Coversyl and its generic perindopril is available in strengths of: 2mg, 4mg, 8mg, Plus, Plus LD, and Plus HD.

Perindopril belongs to the class of medications called angiotensin converting enzyme (ACE) inhibitors which are used to treat high blood pressure, prevent mild-to-moderate congestive heart failure, or decrease the risk of further heart attack occurrences in people with coronary artery disease. High blood pressure adds to the workload of the heart and arteries. If the additional workload is untreated or left unmanaged, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart or kidney failure.

Perindopril works to relax veins and arteries allowing for smoother blood flow thus lower blood pressure by preventing an enzyme in the body from producing angiotensin II, a substance that narrows blood vessels. As a result, blood vessels stay relaxed allowing for an adequate supply of blood and oxygen to the heart that will lower blood pressure.

To treat high blood pressure or after a heart attack, the usual starting dose of perindopril is 4 mg taken once daily. The dose may be increased after 2 weeks up to a maximum of 8 mg once daily depending on blood pressure control. Perindopril may be used alone or in combination with other medications to reduce blood pressure.

When used to treat congestive heart failure, the starting dose of perindopril is 2 mg. It may then be increased to 4 mg once daily depending on the effect of the medication and side effects.

For best results, the tablets should be taken before a meal and on an empty stomach. Once-daily doses should be taken in the morning before breakfast. Seniors and people with kidney disease may require smaller doses.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones given here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by the doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children. Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Do not take perindopril if you:

• are allergic to perindopril or any ingredients of the medication

• are pregnant or may become pregnant

• are breast-feeding

• are taking the medication sacubitril-valsartan

• have been diagnosed with hereditary angioedema

• have had angioedema (a serious allergic reaction which causes the area around the throat and tongue to swell) after taking any other ACE inhibitors (e.g., captopril, enalapril, ramipril)

• have narrowing of the arteries in the kidneys

• have diabetes or kidney disease and are taking aliskiren

• have galactose intolerance, Lapp lactase deficiency (a rare hereditary condition), or glucose-galactose malabsorption​

• are receiving dialysis or any other type of blood filtration

• are on any of the following medications:

  • acetazolamide

  • acetylsalicylic acid (ASA)

  • aldesleukin

  • aliskiren

  • allopurinol

  • alpha-agonists (e.g., clonidine, methyldopa)

  • alpha-blockers (e.g., alfuzosin, doxazosin, tamsulosin)

  • amifostine

  • amiodarone

  • amphetamines (e.g., dextroamphetamine, lisdexamfetamine)

  • other angiotensin converting enzyme inhibitors (ACEIs; captopril, enalapril, ramipril)

  • angiotensin receptor blockers (ARBs; e.g., candesartan, irbesartan, losartan)

  • antipsychotics (e.g., clozapine, olanzapine, quetiapine, risperidone)

  • apomorphine

  • azathioprine

  • barbiturates (e.g., butalbital, pentobarbital, phenobarbital)

  • beta-adrenergic blockers (e.g., atenolol, propranolol, sotalol)

  • brimonidine

  • bromocriptine

  • calcium channel blockers (e.g., amlodipine, diltiazem, nifedipine, verapamil)

  • conivaptan

  • dexmethylphenidate

  • diabetes medications (e.g., canagliflozin, glyburide, insulin, metformin, saxagliptin)

  • digoxin

  • diuretics (water pills; e.g., furosemide, amiloride, spironolactone, triamterene)

  • drospirenone

  • duloxetine

  • eplerenone

  • everolimus

  • gold salts

  • grass pollen allergen extract

  • guanfacine

  • heparin

  • iron dextran

  • levodopa

  • lithium

  • low molecular weight heparins (e.g., dalteparin, enoxaparin, tinzaparin)

  • medications that increase blood levels of potassium (e.g., potassium chloride, salt substitutes containing potassium)

  • metformin

  • methylphenidate

  • monoamine oxidase inhibitors (MAOIs; e.g., moclobemide, phenelzine, rasagiline, selegiline, tranylcypromine)

  • morphine

  • nabilone

  • nitrates (e.g., isosorbide dinitrate, isosorbide mononitrate)

  • nonsteroidal anti-inflammatory medications (NSAIDs; e.g., diclofenac, ibuprofen, indomethacin, ketorolac)

  • obinutuzumab

  • pentoxifylline

  • phosphodiesterase 5 inhibitors (e.g., sildenafil, tadalafil, vardenafil)

  • pramipexole

  • pregabalin

  • riociguat

  • ropinirole

  • rotigotine

  • sacubitril

  • sirolimus

  • sodium phosphates

  • tacrolimus

  • temsirolimus

  • tizanidine

  • tolvaptan

  • trimethoprim

  • yohimbine

Possible side effects include:

• cold symptoms (e.g., nasal congestion, runny nose, cough, sore throat)

• cough (dry, persistent)

• diarrhea

• difficulty maintaining an erection

• dizziness

• drowsiness

• feeling weak

• headache

• loss of taste

• metallic taste in mouth

• swelling of the hands, feet, or ankles

• trouble sleeping

• unusual tiredness

• chest pain

• numbness or tingling in the fingers or toes

• pounding or irregular heartbeat

• ringing in the ears

• severe abdominal pain with or without nausea and vomiting

• signs of bleeding (e.g., unusual nosebleeds, blood in urine, coughing blood, bruising easily, cuts that won't stop bleeding)

• signs of depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)

• signs of fluid and electrolyte imbalance (e.g., drowsiness, muscle pain or cramps, weakness, irregular heartbeat)

• signs of infection (symptoms may include fever or chills, severe diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness)

• signs of kidney problems (e.g., increased urination at night, decreased urine production, blood in the urine, change of urine colour)

• signs of low blood pressure (e.g., dizziness, lightheadedness, fainting)

• signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)

• signs of too much potassium in the body (e.g., confusion; irregular heartbeat; nervousness; numbness or tingling in hands, feet, or lips; shortness of breath or difficulty breathing; weakness or heaviness of legs)

• skin rash, with or without itching, skin blisters, fever, or joint pain

• swelling of the hands, feet, or ankles

• worsening symptoms of psoriasis

© 2023 Arcedpharmas is the registered trademark used under license from YYOUNG Trademark Ltd. All material copyright MediResource Inc. 1996 – 2023. Terms and conditions of use. The contents herein are for informational purposes only. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Source: www.medbroadcast.com/drug/getdrug/Apo-Perindopril

Disclaimers: The images used on this website are for reference only. The product images shown may represent the range of product, or be for illustration purposes only and may not be an exact representation of the product.

Any returns of a product due to customer dissatisfaction will need to comply with the © 2023 Arcedpharmas Returns Policy.

CRESTOR 40MG BLSPK  (30 TABLETS)

Generic Name: rosuvastatin
Brand Name: Crestor
Drug class: HMG-CoA Reductase Inhibitors, Lipid-Lowering Agents, Statins

WHAT IS THE DOSAGE OF THIS MEDICATION?

Crestor and its generic rosuvastatin is available in the strength of 5 mg, 10 mg, 20 mg, and 40 mg tablets.

WHAT IS THIS MEDICATION USED FOR?

Rosuvastatin belongs to the group of medications known as HMG CoA reductase inhibitors ("statins"). It is used, along with a healthy diet and exercise program, to improve cholesterol levels by decreasing low-density lipoprotein (LDL) cholesterol ('bad cholesterol') and triglycerides in the blood, and increasing high-density lipoprotein (HDL) cholesterol ('good cholesterol') in the blood. It is also used to treat people who have certain inherited cholesterol disorders.

Rosuvastatin works by blocking the enzyme that helps make cholesterol in the body. People with high blood cholesterol levels have a higher risk of heart diseases such as heart attacks. When cholesterol levels are lowered with a combination of medication, diet, and exercise, the risk of heart disease is lowered. It takes 2 to 4 weeks to see the maximum effect of this medication on cholesterol levels in blood tests.

It can also be used to reduce the risk of heart attacks, stroke, and angioplasty for people who have at least 2 risk factors for cardiovascular disease.

Before starting rosuvastatin, you should be following a cholesterol-lowering diet. If appropriate, a program of weight control and physical exercise should also be implemented.

The recommended dose of rosuvastatin ranges between 5 mg and 40 mg once daily. For most people, the usual recommended starting dose of rosuvastatin is 10 mg once daily. If necessary, the dose may be increased to a maximum of 40 mg daily. People who require the maximum dose of 40 mg per day should consult a specialist.

For children 10 to 17 years of age, who have inherited cholesterol disorders, the recommended starting dose is 5 mg taken once daily. Your doctor may increase this dose to a maximum of 10 mg daily, depending on the effectiveness of the medication and how well it is tolerated.

For people with severely reduced liver function, the maximum daily dose is 20 mg.

For people with severely reduced kidney function, the starting dose should be 5 mg daily and the maximum daily dose is 10 mg.

A starting dose of 5 mg daily is recommended for people of Asian descent (Chinese, Filipino, Japanese, Korean, Vietnamese, or Asian-Indian origin) and those who have severe kidney problems. This low dose should also be considered for people who do not need aggressive cholesterol-lowering effects and for people who may be at a greater risk of experiencing muscle-related problems.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Rosuvastatin may be taken in the morning or in the evening, with or without food.

It is very important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and carry on with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children. Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

WHO SHOULD NOT TAKE THIS MEDICATION

Do not take rosuvastatin if you:

• are allergic to rosuvastatin or any ingredients of the medication

• are pregnant

• are breast-feeding

• are taking cyclosporine

• are taking the medications sofosbuvir/velpatasvir/voxilaprevir for chronic hepatitis C virus infection

• have active liver disease or have unexplained increases in certain liver function tests

Do not take the 40 mg strength of rosuvastatin if you:

• are of Asian descent (Chinese, Filipino, Japanese, Korean, Vietnamese, or Asian-Indian origin)

• are taking niacin or a fibrate (e.g., gemfibrozil, fenofibrate)

• have alcoholism or consume large quantities of alcohol

• have an inherited muscle disorder or a family history of these disorders

• have had muscle damage with another statin medication (e.g., lovastatin, pravastatin, simvastatin)

• have hypothyroidism (an underactive thyroid gland)

• have other medical conditions or are taking other medications that would increase blood levels of rosuvastatin (check with your doctor or pharmacist to see if this applies to you)

• have severely reduced liver or kidney function

  ---

POTENTIAL INTERACTION WITH OTHER MEDICATION

The following medications could potentially interact with rosuvastatin:

• antacids (if taken within 2 hours of taking rosuvastatin) (e.g., aluminum hydroxide, calcium carbonate, magnesium hydroxide)

• apalutamide

• bezafibrate

• carbamazepine

• clopidogrel

• cobicistat

• colchicine

• cyclosporine

• dronedarone

• elagolix

• eltrombopag

• eslicarbazepine

• fenofibrate

• gemfibrozil

• hepatitis C antivirals (e.g., glecaprevir and pibrentasvir, grazoprevir, ledipasvir, sofosbuvir, velpatasvir, voxilaprevir)

• HIV protease inhibitors (e.g., atazanavir, indinavir, ritonavir, saquinavir)

• itraconazole

• letermovir

• niacin (nicotinic acid)

• niacinamide

• pazopanib

• raltegravir

• regorafenib

• repaglinide

• rifampin

• other "statin" anti-cholesterol medications (e.g., atorvastatin, lovastatin, simvastatin)

• teriflunomide

• tolvaptan

• trabectedin

• warfarin

WHAT ARE THE SIDE EFFECTS OF THIS MEDICATION?

Possible side effects include:

• constipation

• decreased sexual ability

• difficulty sleeping

• dizziness

• headache

• nausea

• nightmares

• stomach pain

• breast enlargement

• confusion

• hives

• itching

• numbness, tingling, weakness, or pain in the hands or feet

• persistent cough, with or without shortness of breath

• poor memory

• signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don't stop bleeding)

• signs of depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)

• skin rash

• symptoms of high blood sugar (e.g., frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, fruity breath odour)

• symptoms of liver damage (such as yellow skin or eyes, abdominal pain, dark urine, clay-coloured stools, loss of appetite, nausea and vomiting, or itching)

• symptoms of muscle damage (unexplained muscle pain, tenderness or weakness, or brown or discoloured urine – especially if you also have a fever or a general feeling of being unwell)

• weakness

© 2023 Arcedpharmas is the registered trademark used under license from YYOUNG Trademark Ltd. All material copyright MediResource Inc. 1996 – 2023. Terms and conditions of use. The contents herein are for informational purposes only. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Source: www.medbroadcast.com/drug/getdrug/ACT-Rosuvastatin

Disclaimers: The images used on this website are for reference only. The product images shown may represent the range of product, or be for illustration purposes only and may not be an exact representation of the product.

Any returns of a product due to customer dissatisfaction will need to comply with the © 2023 Arcedpharmas Returns Policy.