COVERSYL PLUS 4MG/1.25MG BLSPK 30 TB

COVERSYL PLUS 4MG/1.25MG (30 TABS)

Generic Name: perindopril - indapamide
Brand Name: Coversyl Plus
Drug class: Angiotensin Converting Enzyme Inhibitors

Coversyl and its generic perindopril is available in strengths of: 2mg, 4mg, 8mg, Plus, Plus LD, and Plus HD.

Coversyl Plus is a combination of two medications (perindopril and indapamide) used to treat adults with mild-to-moderate high blood pressure. High blood pressure adds to the workload of the heart and arteries. If the additional workload is untreated or left unmanaged, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart or kidney failure.

Perindopril belongs to the class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by relaxing blood vessels and helping the heart to pump blood that carries oxygen to the different parts of the body more efficiently. Indapamide belongs to the class of medications called diuretics or "water pills," which help control blood pressure by getting rid of excess salt and water.

This medication should not be given to anyone who is in a coma due to reduced liver function.

This combination medication is used to make dosing more convenient for people who need to take both of these medications (perindopril and indapamide). The dose of the combination medication depends on the doses of the individual medications the person needs.

The usual recommended dose of this medication is one tablet taken once a day, preferably in the morning before a meal.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature and keep it out of the reach of children. Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Do not take perindopril - indapamide if you:

are allergic to perindopril, indapamide, or any ingredients of the medication
are allergic to sulfa (sulfonamide) medications (e.g., sulfamethoxazole)
are pregnant or are planning to become pregnant or are not using effective birth control
are breast-feeding
are taking the medication sacubitril/valsartan
have decreased kidney function or are unable to pass urine
have untreated high or low potassium
have had angioedema (a serious allergic reaction that causes the area around the throat and tongue to swell) after taking any ACE inhibitors (e.g., captopril, ramipril)
have diabetes or kidney disease and are taking aliskiren
have galactose intolerance (a rare hereditary disease) or lactose intolerance
have hereditary angioedema (a serious allergic reaction which causes swelling of the hands, feet, ankles, face, lips, tongue, or throat) or have angioedema with no known cause
have severely decreased liver function or have hepatic encephalopathy
are taking other medications that affect heart rhythm
have bilateral renal artery stenosis or renal artery stenosis in a single functioning kidney
are receiving dialysis or any other type of blood filtration
are on any of the following medications:
- acetylsalicylic acid (ASA)
- aclidinium
- alcohol
- aldesleukin
- aliskiren
- allopurinol
- alpha-agonists (e.g., clonidine, methyldopa)
- alpha-blockers (e.g., alfuzosin, doxazosin, tamsulosin)
- amifostine
- amiodarone
- amphetamines (e.g., dextroamphetamine, lisdexamfetamine)
- anagrelide
- other angiotensin converting enzyme inhibitors (ACEIs; e.g., captopril, lisinopril, ramipril)
- angiotensin receptor blockers (ARBs; e.g., candesartan, irbesartan, losartan)
- antihistamines (e.g., cetirizine, doxylamine, diphenhydramine, hydroxyzine, loratadine)
- antipsychotics (e.g., chlorpromazine, clozapine, haloperidol, olanzapine, quetiapine, risperidone, thioridazine, ziprasidone)
- apomorphine
- atropine
- azathioprine
- azelastine
- barbiturates (e.g., phenobarbital, secobarbital, butalbital)
- belladonna
- benztropine
- beta-adrenergic blockers (e.g., metoprolol, propranolol)
- beta-2 agonists (e.g., formoterol, salmeterol)
- bisacodyl
- brimonidine
- bromocriptine
- calcium channel blockers (e.g., amlodipine, diltiazem, nifedipine)
- calcium supplements (e.g., calcium carbonate, calcium citrate)
- carbamazepine
- chloroquine
- cholestyramine
- clidinium
- colestipol
- conivaptan
- cyclobenzaprine
- cyclophosphamide
- darifenacin
- dexmethylphenidate
- diabetes medications (e.g., dapagliflozin, insulin, glyburide, linagliptin, liraglutide, metformin, metformin, rosiglitazone)
- digoxin
- disopyramide
- diuretics (water pills; e.g., furosemide, amiloride, spironolactone, triamterene)
- domperidone
- dronedarone
- drospirenone
- duloxetine
- eplerenone
- everolimus
- flavoxate
- flecainide
- gold salts (e.g., sodium aurothiomalate)
- ginger
- grass pollen allergen extract
- glycopyrrolate
- heparin
- inhaled corticosteroids (e.g., budesonide, ciclesonide, fluticasone)
- ipratropium
- ivabradine
- iron dextran
- iron supplements
- ketotifen
- levodopa
- licorice
- lithium
- low-molecular-weight heparins (LMWH) (e.g., dalteparin, enoxaparin, tinzaparin)
- macrolide antibiotics (e.g., azithromycin, clarithromycin, erythromycin)
- medications that increase blood levels of potassium (e.g., potassium supplements, salt replacements containing potassium, spironolactone, triamterene, amiloride)
- methadone
- methylphenidate
- minoxidil
- multivitamins/minerals with ADE
- monoamine oxidase inhibitors (MAOIs; e.g., moclobemide, phenelzine, rasagiline, selegiline, tranylcypromine)
- nabilone
- narcotic pain relievers (e.g., morphine, codeine)
- nitrates (e.g., nitroglycerin, isosorbide dinitrate, isosorbide mononitrate)
- nonsteroidal anti-inflammatory drugs (NSAIDs; e.g., ibuprofen, indomethacin, naproxen)
- obinutuzumab
- oral corticosteroids (e.g., dexamethasone, hydrocortisone, prednisone)
- orphenadrine
- oxcarbazepine
- oxybutynin
- pentoxifylline
- phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil, vardenafil)
- pramipexole
- pregabalin
- procainamide
- quinidine
- quinolone antibiotics (e.g., ciprofloxacin, levofloxacin)
- riociguat
- ropinirole
- rotigotine
- sacubitril
- scopolamine
- selective serotonin reuptake inhibitors (SSRIs; e.g., citalopram, fluoxetine, paroxetine, sertraline)
- senna
- sirolimus
- sodium phosphate
- solifenacin
- sotalol
- tacrolimus
- temsirolimus
- tetrabenazine
- tiotropium
- tizanidine
- tolterodine
- tolvaptan
- topiramate
- tricyclic antidepressants (e.g., amitriptyline, imipramine)
- trimethoprim
- tyrosine kinase inhibitors (e.g., lapatinib, nilotinib, pazopanib, sunitinib, vandetanib)
- umeclidinium
- vitamin D analogues (e.g., alfacalcidol, calcitriol, cholecalciferol)
- yohimbine

This medication should not be given to anyone who is in a coma due to reduced liver function.

Possible side effects include:

abdominal pain
cold-like symptoms
constipation
cough (dry, persistent)
diarrhea
dizziness
drowsiness
dry mouth
headache
loss of appetite
nausea
pins and needles sensation
spinning sensation
sensitivity to sunlight
sleep disturbances
sweating
taste changes (e.g., metallic taste)
tiredness
vomiting
weakness
discolouration, numbness, and pain in fingers or toes
dizziness, lightheadedness, or fainting (signs of low blood pressure)
joint pain (e.g., toe pain may be a sign of gout)
mood swings
muscle cramps or unexplained muscle pain
signs of anemia (low red blood cells; e.g., dizziness, pale skin, unusual tiredness or weakness, shortness of breath)
signs of bleeding (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don't stop bleeding)
signs of infection (symptoms may include fever or chills, severe diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness)
signs of high blood calcium levels (e.g., loss of appetite, nausea, vomiting, constipation or stomach pain)
signs of kidney problems (e.g., decreased urination, nausea, vomiting, swelling of legs, hands, fatigue)
signs of liver problems (e.g., abdominal pain, nausea or vomiting, itching of skin, yellow eyes or skin)
signs of too much or too little potassium in the body (e.g., dry mouth; increased thirst; irregular heartbeat; mood or mental changes; muscle cramps or pain; numbness or tingling in hands, feet, or lips; weak pulse; weakness or heaviness of legs)
signs of muscle damage (e.g., unexplained muscle pain, tenderness or weakness, or brown or discoloured urine)
skin rash, with or without itching, fever, or joint pain
stomach pain (severe) with nausea and vomiting
swelling of hands, ankles or feet
symptoms of high blood sugar (e.g., frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, fruity breath odour)
symptoms of inappropriate anti-diuretic hormone secretion (SIADH; dark-coloured urine, nausea, vomiting, muscle cramps, confusion, seizures)
symptoms of irregular heartbeat (e.g., chest pain, dizziness, rapid, pounding heartbeat, shortness of breath)
worsening psoriasis
vision changes

© 2023 Arcedpharmas is the registered trademark used under license from YYOUNG Trademark Ltd. All material copyright MediResource Inc. 1996 – 2023. Terms and conditions of use. The contents herein are for informational purposes only. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Source: www.medbroadcast.com/drug/getdrug/Apo-Perindopril

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CRESTOR 40MG BLSPK (30 TABLETS)

Generic Name: rosuvastatin
Brand Name: Crestor
Drug class: HMG-CoA Reductase Inhibitors, Lipid-Lowering Agents, Statins

WHAT IS THE DOSAGE OF THIS MEDICATION?

Crestor and its generic rosuvastatin is available in the strength of 5 mg, 10 mg, 20 mg, and 40 mg tablets.

WHAT IS THIS MEDICATION USED FOR?

Rosuvastatin belongs to the group of medications known as HMG CoA reductase inhibitors ("statins"). It is used, along with a healthy diet and exercise program, to improve cholesterol levels by decreasing low-density lipoprotein (LDL) cholesterol ('bad cholesterol') and triglycerides in the blood, and increasing high-density lipoprotein (HDL) cholesterol ('good cholesterol') in the blood. It is also used to treat people who have certain inherited cholesterol disorders.

Rosuvastatin works by blocking the enzyme that helps make cholesterol in the body. People with high blood cholesterol levels have a higher risk of heart diseases such as heart attacks. When cholesterol levels are lowered with a combination of medication, diet, and exercise, the risk of heart disease is lowered. It takes 2 to 4 weeks to see the maximum effect of this medication on cholesterol levels in blood tests.

It can also be used to reduce the risk of heart attacks, stroke, and angioplasty for people who have at least 2 risk factors for cardiovascular disease.

Before starting rosuvastatin, you should be following a cholesterol-lowering diet. If appropriate, a program of weight control and physical exercise should also be implemented.

The recommended dose of rosuvastatin ranges between 5 mg and 40 mg once daily. For most people, the usual recommended starting dose of rosuvastatin is 10 mg once daily. If necessary, the dose may be increased to a maximum of 40 mg daily. People who require the maximum dose of 40 mg per day should consult a specialist.

For children 10 to 17 years of age, who have inherited cholesterol disorders, the recommended starting dose is 5 mg taken once daily. Your doctor may increase this dose to a maximum of 10 mg daily, depending on the effectiveness of the medication and how well it is tolerated.

For people with severely reduced liver function, the maximum daily dose is 20 mg.

For people with severely reduced kidney function, the starting dose should be 5 mg daily and the maximum daily dose is 10 mg.

A starting dose of 5 mg daily is recommended for people of Asian descent (Chinese, Filipino, Japanese, Korean, Vietnamese, or Asian-Indian origin) and those who have severe kidney problems. This low dose should also be considered for people who do not need aggressive cholesterol-lowering effects and for people who may be at a greater risk of experiencing muscle-related problems.

Rosuvastatin may be taken in the morning or in the evening, with or without food.

It is very important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and carry on with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children. Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

WHO SHOULD NOT TAKE THIS MEDICATION

Do not take rosuvastatin if you:

are allergic to rosuvastatin or any ingredients of the medication
are pregnant
are breast-feeding
are taking cyclosporine
are taking the medications sofosbuvir/velpatasvir/voxilaprevir for chronic hepatitis C virus infection
have active liver disease or have unexplained increases in certain liver function tests

Do not take the 40 mg strength of rosuvastatin if you:

are of Asian descent (Chinese, Filipino, Japanese, Korean, Vietnamese, or Asian-Indian origin)
are taking niacin or a fibrate (e.g., gemfibrozil, fenofibrate)
have alcoholism or consume large quantities of alcohol
have an inherited muscle disorder or a family history of these disorders
have had muscle damage with another statin medication (e.g., lovastatin, pravastatin, simvastatin)
have hypothyroidism (an underactive thyroid gland)
have other medical conditions or are taking other medications that would increase blood levels of rosuvastatin (check with your doctor or pharmacist to see if this applies to you)
have severely reduced liver or kidney function

POTENTIAL INTERACTION WITH OTHER MEDICATION

The following medications could potentially interact with rosuvastatin:

antacids (if taken within 2 hours of taking rosuvastatin) (e.g., aluminum hydroxide, calcium carbonate, magnesium hydroxide)
apalutamide
bezafibrate
carbamazepine
clopidogrel
cobicistat
colchicine
cyclosporine
dronedarone
elagolix
eltrombopag
eslicarbazepine
fenofibrate
gemfibrozil
hepatitis C antivirals (e.g., glecaprevir and pibrentasvir, grazoprevir, ledipasvir, sofosbuvir, velpatasvir, voxilaprevir)
HIV protease inhibitors (e.g., atazanavir, indinavir, ritonavir, saquinavir)
itraconazole
letermovir
niacin (nicotinic acid)
niacinamide
pazopanib
raltegravir
regorafenib
repaglinide
rifampin
other "statin" anti-cholesterol medications (e.g., atorvastatin, lovastatin, simvastatin)
teriflunomide
tolvaptan
trabectedin
warfarin

WHAT ARE THE SIDE EFFECTS OF THIS MEDICATION?

Possible side effects include:

constipation
decreased sexual ability
difficulty sleeping
dizziness
headache
nausea
nightmares
stomach pain
breast enlargement
confusion
hives
itching
numbness, tingling, weakness, or pain in the hands or feet
persistent cough, with or without shortness of breath
poor memory
signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don't stop bleeding)
signs of depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
skin rash
symptoms of high blood sugar (e.g., frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, fruity breath odour)
symptoms of liver damage (such as yellow skin or eyes, abdominal pain, dark urine, clay-coloured stools, loss of appetite, nausea and vomiting, or itching)
symptoms of muscle damage (unexplained muscle pain, tenderness or weakness, or brown or discoloured urine – especially if you also have a fever or a general feeling of being unwell)
weakness

© 2023 Arcedpharmas is the registered trademark used under license from YYOUNG Trademark Ltd. All material copyright MediResource Inc. 1996 – 2023. Terms and conditions of use. The contents herein are for informational purposes only. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Source: www.medbroadcast.com/drug/getdrug/ACT-Rosuvastatin