BASAGLAR CARTRIDGE 100U/ML  (5X3ML)

Generic Name: insulin glargine
Brand Name: Basaglar
Drug Class: Insulin

Basaglar is available in two formats:

• A cartridge containing 5x3 mL. Each mL of sterile solution contains 100 units of insulin glargine.

• A KwikPen containing 5x3 mL. Each mL of sterile solution contains 100 units of insulin glargine.

Insulin is a naturally occurring hormone made by the pancreas that helps our body use or store the glucose (sugar) it gets from food. For people with diabetes, either the pancreas does not make enough insulin to meet the body's requirements, or the body cannot properly use the insulin that is made. As a result, glucose cannot be used or stored properly and accumulates in the bloodstream. Insulin injected under the skin helps to lower blood glucose levels.

There are many different types of insulin and they are absorbed at different rates and work for varying periods of time. Insulin glargine is an extended, long-acting insulin. It takes about 90 minutes to begin working after injection, and it stops working after about 24 hours. After injection, insulin glargine is released slowly and constantly into the bloodstream.

Your required dose of insulin depends on how much natural insulin your pancreas is producing and how well your body is able to use the insulin. Your doctor or diabetes educator will determine the appropriate dose for you according to various lifestyle factors and the blood glucose values obtained while monitoring your blood glucose.

Your dose of insulin should be injected subcutaneously (under the skin) to the stomach, upper arm, or thigh regions, exactly as instructed by your doctor or diabetes educator. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems from the injections. Do not inject insulin glargine into the vein and do not use insulin glargine in insulin infusion pumps. The dose of insulin is measured in international units (IU). Each 1 mL of insulin contains 100 IU. Insulin glargine is injected under the skin once daily. In addition to insulin glargine, doses of a fast-acting insulin are usually used to control the impact of food intake on blood sugar levels during the day. There are many variations of insulin dosing.

Insulin glargine should be clear and colourless. Do not use the insulin if you notice anything unusual in the appearance of the solution, such as cloudiness, discoloration, or clumping. It is not necessary to shake or rotate the vial before use. It should not be mixed with other insulins.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is very important to use this medication exactly as prescribed by your doctor. The timing of insulin with respect to your meals is crucial to keeping blood sugar under control and preventing unwanted side effects.

Keep unopened bottles of insulin in the refrigerator until needed. They may be used until the expiry date on the label. Never allow insulin to freeze. Insulin that is currently in use may be kept at room temperature for no more than 28 days and then discarded. Do not expose insulin to extremely hot temperatures or to sunlight. Keep insulin out of the reach of children.

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