PROPRANOLOL 10MG 100 TB

PROPRANOLOL 10MG (100 TABLETS)

Generic Name: propranolol
Brand Name: Inderal
Drug classes: Group II antiarrhythmics, Non-cardioselective beta blockers

Inderal and its generic propranolol is available in the strength of 10 mg, 40 mg, and 80 mg tablets.

Propranolol belongs to the class of medications called beta-blockers and is used to control cardiovascular diseases, including treat high blood pressure, prevent chest pain (angina), reduce the risk of more heart problems after a heart attack (myocardial infarction), treat certain types of abnormal heart rhythms, and prevent heart failure. High blood pressure adds to the workload of the heart and arteries. If the additional workload is untreated or left unmanaged, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart or kidney failure.

Propranolol works by blocking a neurotransmitter called catecholamine (adrenaline) from binding to β1-adrenergic receptors, which are mainly found in the heart muscle cells and heart conduction tissue. The union between catecholamine and β1-adrenergic receptors activates greater cardiovascular workload resulting in an increase in blood pressure, heart rate, and oxygen demand. By propranolol’s competitive inhibition of β1-adrenergic receptors, the stimuli that is catecholamine is negated from activating greater cardiovascular output. Thus, blood pressure and oxygen demand decreases.

Propranolol is also used for the prevention of migraines. It is also used, in combination with other medications, to manage the symptoms caused by pheochromocytoma (a tumour of the adrenal glands).

The recommended adult dose of propranolol varies widely according to the condition being treated and circumstances of the person taking the medication. Propranolol may be taken with or without food. Do not stop taking this medication suddenly unless you have talked with your doctor first.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones given here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture and keep it out of the reach of children. Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Do not take propranolol if you:

are allergic to propranolol or any ingredients of the medication
are in cardiogenic shock
are prone to low blood glucose
have a severely slow heart rate
have allergic rhinitis during the pollen season
have asthma or severe chronic obstructive respiratory diseases (e.g., emphysema, chronic bronchitis)
have congestive heart failure
have right ventricular failure secondary to pulmonary hypertension (excessive blood pressure in the lungs)
have serious heart block (second- and third-degree AV block) or sick sinus syndrome
have severe circulatory disorders
have a condition where the blood is acidic
have severely decreased blood pressure
have untreated pheochromocytoma (a tumour of the adrenal glands)
have Prinzmetal angina (a condition that causes angina or chest pain at rest)
have uncontrolled heart failure

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Inform your doctor about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

are on any of the following medications:
- abiraterone
- alcohol
- aldesleukin
- aliskiren
- alpha agonists (e.g., clonidine, methyldopa)
- alpha blockers (e.g., alfuzosin, doxazosin, tamsulosin)
- amiodarone
- amphetamines (e.g., dextroamphetamine, lisdexamphetamine)
- angiotensin-converting enzyme inhibitors (ACEIs; captopril, ramipril)
- angiotensin receptor blockers (ARBs; e.g., candasartan, irbesartan, losartan)
- anti-malarial medications (e.g., chloroquine, hydroxychloroquine, mefloquine, primaquine)
- antipsychotic medications (e.g., chlorpromazine, clozapine, haloperidol, risperidone)
- asunaprevir
- barbiturates (e.g., butalbital, pentobarbital phenobarbital)
- beta-2 agonists (e.g., salbutamol, formoterol, terbutaline, salmeterol)
- brimonidine
- bupropion
- calcium channel blockers (e.g., amlodipine, diltiazem, nifedipine, verapamil)
- cannabis
- carbamazepine
- celecoxib
- certain protein kinase inhibitors (e.g., bosutinib, ceritinib, nilotinib, pazopanib
- cetirizine
- cholestyramine
- cimetidine
- clobazam
- cobicistat
- colchicine
- colestipol
- cyclosporine
- cyproterone
- dabigatran
- darifenacin
- deferasirox
- delavirdine
- dexamethasone
- diazoxide
- digoxin
- diphenhydramine
- dipyridamole
- disopyramide
- diuretics (water pills; e.g., furosemide, hydrochlorothiazide, triamterene)
- donepezil
- dronedarone
- epinephrine
- ergot alkaloids (e.g., dihydroergotamine, methysergide)
- estrogens (e.g., conjugated estrogen, estradiol, ethinyl estradiol)
- fentanyl
- fingolimod
- galantamine
- gemfibrozil
- “gliptin” diabetes medications (e.g., linagliptin, saxagliptin, sitagliptin)
- grass pollen allergen extract
- guanfacine
- HIV protease inhibitors (e.g., indinavir, nelfinavir, ritonavir, saquinavir)
- hydralazine
- hydrocortisone
- insulin
- isoniazid
- ivermectin
- ketoconazole
- lacosamide
- lanreotide
- levodopa
- loperamide
- medications to treat cancer (e.g., brentuximab, daunorubicin, doxorubicin, etoposide, idarubicin, imatinib, irinotecan, methotrexate, paclitaxel, temsirolimus, vinblastine, vincristine)
- methadone
- methylphenidate
- mexiletine
- minoxidil
- mirabegron
- naloxegol
- nitrates (e.g., nitroglycerin, isosorbide dinitrate, isosorbide mononitrate)
- nonsteroidal anti-inflammatory drugs (NSAIDs; e.g., diclofenac, ibuprofen, ketorolac, naproxen)
- octreotide
- ondansetron
- other beta-adrenergic blockers (e.g., atenolol, propranolol, sotalol)
- pasireotide
- peginterferon alfa-2b
- pentoxiphylline
- phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil, vardenafil)
- pilocarpine
- primidone
- propafenone
- prucalopride
- quinidine
- quinine
- quinolone antibiotics (e.g., ciprofloxacin, norfloxacin, moxifloxacin)
- rifampin
- rivaroxaban
- rivastigmine
- rizatriptan
- romidepsin
- St. John's wort
- selective serotonin reuptake inhibitors (SSRIs; e.g., citalopram, fluoxetine, fluvoxamine paroxetine, sertraline)
- sirolimus
- "statin" anti-cholesterol medications (e.g., atorvastatin, lovastatin, simvastatin)
- sulfonylureas (e.g., gliclazide, glyburide, tolbutamide)
- tacrolimus
- terfenadine
- teriflunomide
- theophyllines (e.g., theophylline, aminophylline, oxtriphylline)
- ticlopidine
- tizanidine
- tolvaptan
- tranylcypromine
- tricyclic antidepressants (e.g., imipramine, desipramine, clomipramine)
- warfarin
- zolmitriptan

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

This is not a complete list of possible side effects. If you notice other effects not listed, please contact your doctor or pharmacist.

Possible side effects include:

abdominal pain
diarrhea
dizziness
dry eyes
fatigue
headache
loss of appetite
nausea
nightmares
trouble sleeping
unusual tiredness or weakness
vomiting
breathing difficulty or wheezing
chest pain
cold hands and feet
dizziness when rising from a sitting or lying position (orthostatic hypotension)
hallucinations (hearing or seeing things that aren't there)
memory problems
ringing in the ears
slow heartbeat (especially less than 50 beats per minute)
signs of heart failure (e.g., shortness of breath, fatigue, swelling in legs, ankles, feet)
symptoms of low blood sugar (e.g., cold sweat, cool pale skin, headache, fast heart beat, weakness
symptoms of low blood pressure (e.g., dizziness, fatigue)
symptoms of Raynaud's phenomenon (numbness and spasm in fingers followed by warmth and pain)
unusual bleeding or bruising
vision changes

© 2023 Arcedpharmas is the registered trademark used under license from YYOUNG Trademark Ltd. All material copyright MediResource Inc. 1996 – 2023. Terms and conditions of use. The contents herein are for informational purposes only. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Source: www.medbroadcast.com/drug/getdrug/Dom-Propranolol

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CRESTOR 40MG BLSPK (30 TABLETS)

Generic Name: rosuvastatin
Brand Name: Crestor
Drug class: HMG-CoA Reductase Inhibitors, Lipid-Lowering Agents, Statins

WHAT IS THE DOSAGE OF THIS MEDICATION?

Crestor and its generic rosuvastatin is available in the strength of 5 mg, 10 mg, 20 mg, and 40 mg tablets.

WHAT IS THIS MEDICATION USED FOR?

Rosuvastatin belongs to the group of medications known as HMG CoA reductase inhibitors ("statins"). It is used, along with a healthy diet and exercise program, to improve cholesterol levels by decreasing low-density lipoprotein (LDL) cholesterol ('bad cholesterol') and triglycerides in the blood, and increasing high-density lipoprotein (HDL) cholesterol ('good cholesterol') in the blood. It is also used to treat people who have certain inherited cholesterol disorders.

Rosuvastatin works by blocking the enzyme that helps make cholesterol in the body. People with high blood cholesterol levels have a higher risk of heart diseases such as heart attacks. When cholesterol levels are lowered with a combination of medication, diet, and exercise, the risk of heart disease is lowered. It takes 2 to 4 weeks to see the maximum effect of this medication on cholesterol levels in blood tests.

It can also be used to reduce the risk of heart attacks, stroke, and angioplasty for people who have at least 2 risk factors for cardiovascular disease.

Before starting rosuvastatin, you should be following a cholesterol-lowering diet. If appropriate, a program of weight control and physical exercise should also be implemented.

The recommended dose of rosuvastatin ranges between 5 mg and 40 mg once daily. For most people, the usual recommended starting dose of rosuvastatin is 10 mg once daily. If necessary, the dose may be increased to a maximum of 40 mg daily. People who require the maximum dose of 40 mg per day should consult a specialist.

For children 10 to 17 years of age, who have inherited cholesterol disorders, the recommended starting dose is 5 mg taken once daily. Your doctor may increase this dose to a maximum of 10 mg daily, depending on the effectiveness of the medication and how well it is tolerated.

For people with severely reduced liver function, the maximum daily dose is 20 mg.

For people with severely reduced kidney function, the starting dose should be 5 mg daily and the maximum daily dose is 10 mg.

A starting dose of 5 mg daily is recommended for people of Asian descent (Chinese, Filipino, Japanese, Korean, Vietnamese, or Asian-Indian origin) and those who have severe kidney problems. This low dose should also be considered for people who do not need aggressive cholesterol-lowering effects and for people who may be at a greater risk of experiencing muscle-related problems.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Rosuvastatin may be taken in the morning or in the evening, with or without food.

It is very important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and carry on with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children. Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

WHO SHOULD NOT TAKE THIS MEDICATION

Do not take rosuvastatin if you:

are allergic to rosuvastatin or any ingredients of the medication
are pregnant
are breast-feeding
are taking cyclosporine
are taking the medications sofosbuvir/velpatasvir/voxilaprevir for chronic hepatitis C virus infection
have active liver disease or have unexplained increases in certain liver function tests

Do not take the 40 mg strength of rosuvastatin if you:

are of Asian descent (Chinese, Filipino, Japanese, Korean, Vietnamese, or Asian-Indian origin)
are taking niacin or a fibrate (e.g., gemfibrozil, fenofibrate)
have alcoholism or consume large quantities of alcohol
have an inherited muscle disorder or a family history of these disorders
have had muscle damage with another statin medication (e.g., lovastatin, pravastatin, simvastatin)
have hypothyroidism (an underactive thyroid gland)
have other medical conditions or are taking other medications that would increase blood levels of rosuvastatin (check with your doctor or pharmacist to see if this applies to you)
have severely reduced liver or kidney function

POTENTIAL INTERACTION WITH OTHER MEDICATION

The following medications could potentially interact with rosuvastatin:

antacids (if taken within 2 hours of taking rosuvastatin) (e.g., aluminum hydroxide, calcium carbonate, magnesium hydroxide)
apalutamide
bezafibrate
carbamazepine
clopidogrel
cobicistat
colchicine
cyclosporine
dronedarone
elagolix
eltrombopag
eslicarbazepine
fenofibrate
gemfibrozil
hepatitis C antivirals (e.g., glecaprevir and pibrentasvir, grazoprevir, ledipasvir, sofosbuvir, velpatasvir, voxilaprevir)
HIV protease inhibitors (e.g., atazanavir, indinavir, ritonavir, saquinavir)
itraconazole
letermovir
niacin (nicotinic acid)
niacinamide
pazopanib
raltegravir
regorafenib
repaglinide
rifampin
other "statin" anti-cholesterol medications (e.g., atorvastatin, lovastatin, simvastatin)
teriflunomide
tolvaptan
trabectedin
warfarin

WHAT ARE THE SIDE EFFECTS OF THIS MEDICATION?

Possible side effects include:

constipation
decreased sexual ability
difficulty sleeping
dizziness
headache
nausea
nightmares
stomach pain
breast enlargement
confusion
hives
itching
numbness, tingling, weakness, or pain in the hands or feet
persistent cough, with or without shortness of breath
poor memory
signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don't stop bleeding)
signs of depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
skin rash
symptoms of high blood sugar (e.g., frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, fruity breath odour)
symptoms of liver damage (such as yellow skin or eyes, abdominal pain, dark urine, clay-coloured stools, loss of appetite, nausea and vomiting, or itching)
symptoms of muscle damage (unexplained muscle pain, tenderness or weakness, or brown or discoloured urine – especially if you also have a fever or a general feeling of being unwell)
weakness

© 2023 Arcedpharmas is the registered trademark used under license from YYOUNG Trademark Ltd. All material copyright MediResource Inc. 1996 – 2023. Terms and conditions of use. The contents herein are for informational purposes only. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Source: www.medbroadcast.com/drug/getdrug/ACT-Rosuvastatin